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Category: News

Prioritizing Malaria drug targets: a joint effort

By Jessica Konijnenburg15/04/202515/04/2025 Categories: News

TropIQ co-authored a publication in NPJ Drug Discovery on prioritisation of novel molecular targets for malaria drug discovery. Advanced bioinformatics was followed by a heroic effort where a…

Collaborative Study on robust mosquitocidals

By Jessica Konijnenburg09/04/202509/04/2025 Categories: News

TropIQ published a paper resulting from a collaboration with a group of talented colleagues from Burkina Faso and the Netherlands. It builds on the concept of developing isoxazolines…

TropIQ co-authors study on PDE inhibitors

By Jessica Konijnenburg17/12/202417/12/2024 Categories: News

TropIQ scientists co-authored a publication on a new approach to eliminate malaria by blocking cyclic nucleotide catabolism. The paper was published by Science Advances. It describes small molecules…

TropIQ Health Sciences Appoints Michiel van Alst as New CEO

By Jessica Konijnenburg16/08/2024 Categories: News

Nijmegen, August 19th, 2024 – TropIQ Health Sciences is pleased to announce the appointment of Michiel van Alst as the new Chief Executive Officer, effective September 1st, 2024….

TropIQ assays on various Plasmodium life stages contribute to new findings

By Jessica Konijnenburg18/07/202418/07/2024 Categories: News

Recently, our inhibition of liver stage development assay, as well as assays on the sexual parasite stages contributed to the publications of two new articles. Read more here…

Two new publications out

By Jessica Konijnenburg28/07/202328/07/2023 Categories: News

We contributed to a paper on a newly generated reporter line expressing NanoLuciferase. Within two weeks another paper we collaborated on came out about blocking transmission of gametocytes….

Collaboration leads to breakthrough insights in olfactory representation

By Jessica Konijnenburg12/05/202312/05/2023 Categories: News

In a collaboration with Google Research and Osmo, TropIQ contributed to a landmark paper that provides fundamental insights into the relationship between odors. It demonstrates that perceptual similarity…

Miniaturized sporozoite assays identify antimalarials acting on liver schizogony

By Jessica Konijnenburg03/03/202303/03/2023 Categories: News

We investigated how susceptible the early stages of malaria are to chemical treatments, and we created a screening strategy to identify new drugs that can prevent infection. The results are…

New transmission-blocking antibodies found

By Jessica Konijnenburg27/02/2023 Categories: News

TropIQ contributed to two studies that identified novel malaria transmission-blocking monoclonal antibodies from naturally exposed individuals. These studies are published in Immunity. Read more here and here.

TropIQ contributes to arresting growth late in the liver

By Jessica Konijnenburg05/01/202305/01/2023 Categories: News

TropIQ assessed drug sensitivity of a new genetically attenuated malaria parasite that qualifies as a vaccine candidate. The results of these studies have been now been published in…

Digital olfaction predicts mosquito behaviour

By Koen Dechering18/09/202201/11/2022 Categories: News Tags: deep learning, digital olfaction, mosquito, repellents, ticks

From our collaborative work with computational scientists at Google Brain, two exciting preprints have been released on BioRxiv. The first describes an accurate model for odor perception that…

TropIQ presents at the Drug Design and Development seminar in Munich

By Koen Dechering20/06/202201/11/2022 Categories: News

TropIQ will contribute two oral presentations to the 2022 Drug Design and Development Seminar of the German Society for Parasitology: Analysis of tick regurgitation following mechanical, cryogenic and…

MMV, PPSC and TropIQ present a webinar on state of the art in malaria phenotypic screening

By Koen Dechering20/05/202229/07/2022 Categories: News

On June 22nd at 4 pm CET, the Medicines for Malaria Venture, the Pivot Park Screening Centre and TropIQ will present a webinar on their collaborative work in…

Antimalarial MMV’183 is a clinical development candidate

By Koen Dechering20/04/202229/07/2022 Categories: News

TropIQ’s parasitology platform drove the optimisation of pantothenamide compounds that generated MMV’183: a candidate for further clinical development with a new mode of action for treatment of malaria and…

TropIQ publishes innovative mosquito barcoding technology

By Koen Dechering21/12/202129/07/2022 Categories: News

We present a barcoding strategy that enables phenotypic screens of blood-feeding insects against small molecules in microtiter plate-based arrays and apply this to discovery of novel systemic insecticides…

TropIQ awarded large research grant to uncover new mosquito repellents.

By Jessica Konijnenburg21/09/202123/09/2021 Categories: News

  Together with researchers from the University of Washington, TropIQ was awarded 1.3 million USD from the Bill & Melinda Gates Foundation to find new mosquito repellents and…

MalDA prioritises malaria drug targets with TropIQ’s input

By Jessica Konijnenburg17/09/2021 Categories: News

The Malaria Drug Accelerator (MalDA), of which TropIQ is part of, has put together a prioritisation of molecular targets against the malaria parasite Plasmodium falciparum. This publication further…

Our team aids the discovery of a new anti-malarial scaffold.

By Jessica Konijnenburg31/08/202131/08/2021 Categories: News

Due to the continuing rise of resistances against commonly used medication, new anit-malarials are needed to combat the disease. This publication suggests Quinazolinone-2-carboxamide derivatives as a novel malaria…

Review of MalDA’s scientific achievements just released

By Jessica Konijnenburg10/07/202117/09/2021 Categories: News

TropQI has been a part of The Malaria Drug Accelerator (MalDA) since 2018. This consortium consists of 17 research laboratories funded by the Bill and Melinda Gates foundation…

Our liver stage platform supports life cycle profiling for new anti-malarial.

By Jessica Konijnenburg15/06/202131/08/2021 Categories: News

In the battle against malaria new drugs are needed. This publication identified 1-(pyridine-4-yl)pyrrolidine-2-one derivates as a novel, dual stage active (asexual blood stages and liver stage), anti-malaria. read…

TropIQ assists in life cycle profiling of genetically modified chimeric Plasmodium parasite.

By Jessica Konijnenburg21/12/202031/08/2021 Categories: News

To broaden the protective spectrum of a potential whole parasite vaccine against malaria, a chimeric P. falciparum parasite expressing P. falciparum and P. vivax circumsporozoite protein (csp) was…

TropIQ Digitalises Its Discovery Platform with CDD Vault

By Koen Dechering13/10/202014/10/2020 Categories: News

CDD Vault will enable TropIQ Health Sciences to share research results with partners in real time Nijmegen and San Francisco — October 8, 2020 TropIQ Health Sciences, a…

TropIQ contributes to research on malaria vaccine

By Jessica Konijnenburg11/01/202020/02/2020 Categories: News

Production of the primary vaccine candidate Plasmodium falciparum circumsporozoite protein (PfCSP) has proven difficult. This publication for the first time presents a method to produce a soluble, full-length…

Dr. Sheshachalam is joining TropIQ

By Jessica Konijnenburg01/10/201904/10/2019 Categories: News

Dr. Sheshachalam has joined the team as a Scientist. He is an experienced cell biologist with a broad expertise in immunology, molecular biology and drug discovery. He obtained…

TropIQ CEO Koen Dechering gives radio interview on the new malaria drug candidate

By Jessica Konijnenburg19/09/201919/09/2019 Categories: News

Dutch national radio (BNR) has conducted an interview with TropIQ’s CEO Koen Dechering on the recently published novel malaria drug candidate (see publication here). Listen to the interview…

TropIQ-led collaboration develops novel malaria candidate drug

By Jessica Konijnenburg19/09/201922/09/2019 Categories: News

A molecule once designed to cure the skin disease psoriasis appears to be particularly effective against malaria. The antimalarial properties were revealed thanks to one researcher’s inspired hunch…

TropIQ gains new Assistant Scientist

By Jessica Konijnenburg14/09/201904/10/2019 Categories: News

Mrs. De Bruijn is joining the Team as a Assistant Scientist with a wealth of experience in laboratory techniques in the fields of immunology, cell biology and molecular…

TropIQ gains Business Administrator

By Jessica Konijnenburg14/08/201923/08/2019 Categories: News

Mrs. Bijsterveld is joining TropIQ as a Business Administrator with a strong background in financial management in various different fields of work. In her previous affiliations she acquired…

TropIQ at the ICM Weekend School

By Jessica Konijnenburg12/05/201915/05/2019 Categories: News

TropIQ organised a science workshop at the IMC Weekend School. This is a supplementary school on Sundays for children (aged 10-14) from underprivileged neighbourhoods. Through a three-year course,…

New master student at TropIQ

By Jessica Konijnenburg01/05/201917/03/2022 Categories: News

Ms. Sascha Bezemer is joining the team as our new intern. She is a biology master student with specialisation in health and disease. She is enrolled at Wageningen…

TropIQ’s CSO, Robert Sauerwein knighted

By Jessica Konijnenburg26/04/201915/05/2019 Categories: News

Robert Sauerwein, CSO of TropIQ, receives a royal decoration for his pioneering work in malaria vaccinology and drug discovery. He receives the distinction of Knight in the Order…

Scientist Dr. Youri van Nuland is joining the team

By Jessica Konijnenburg01/03/201925/03/2019 Categories: News

Dr. van Nuland is an experienced biochemist with a PhD from Wageningen University in the Netherlands. He is an expert in industrial biotechnology and previously worked on metabolic…

New intern Tom Seijger starting

By Jessica Konijnenburg11/02/201925/03/2019 Categories: News

Mr. Seijger is an undergraduate student at the Saxion University of Applied Sciences in Enschede. He will be doing an internship contributing to projects involving malaria transmission. He…

Dr. Marnix Vlot is joining TropIQ as a postdoctoral scientist.

By Jessica Konijnenburg01/10/201808/10/2018 Categories: News

Dr. Vlot has earned his PhD in molecular microbiology at Wageningen University. He specialises in the molecular mechanism of the CRISPR-Cas gene editing system and will apply his…

Annemijn Grol joins the team.

By Jessica Konijnenburg24/09/201829/10/2018 Categories: News

Ms. Grol is an undergraduate student at the Avans University of Applied Sciences in Breda. She will be doing an internship contributing to our dengue project. She will…

TropIQ on national TV

By Jessica Konijnenburg21/07/201808/10/2018 Categories: News

As a reaction to TropIQs latest study preventing transmission of tropical diseases, published in PNAS in July this year, the Dutch television program EenVandaag (NPO1) presented an item…

Science Magazine writes about TropIQ’s latest publication.

By Jessica Konijnenburg05/07/201826/09/2018 Categories: News

The scientific journal Science report on TropIQ’s finding that dog’s flea and tick medication could prevent the spread of vector borne diseases like malaria and Zika. Click here…

Time Magazine reports on TropIQ’s finding.

By Jessica Konijnenburg04/07/201826/09/2018 Categories: News

Time Magazine has reported on TropIQ’s finding that veterinary drugs have the potential to protect humans from malaria, Zika, and other diseases transmitted by blood feeding insects. Read…

TropIQ publishes description of oral insecticides for vector-borne disease control.

By Jessica Konijnenburg03/07/201812/07/2018 Categories: News

Our research shows that, given to humans, insect killing veterinarian drugs can greatly reduce

Rianne van der Laak is joining TropIQs team as a Research Technician

By Jessica Konijnenburg01/05/201815/05/2018 Categories: News

Ms. van der Laak has previously worked in a variety of companies, which allowed her to

Tonnie Huijs is joining TropIQ as an assistant scientist

By Jessica Konijnenburg16/04/201815/05/2018 Categories: News

Mr. Huijs is an expert in tissue culture and assay development. He gained his experience

TropIQ team contributes to discovery of multiple stage malaria compound

By Jessica Konijnenburg10/03/201828/03/2018 Categories: News

New research, with TropIQ contribution, on a compound series active against malaria asexual and sexual stages was published today. Read more here.

TropIQ hosts the Dutch Malaria Day

By Jessica Konijnenburg16/02/201819/02/2018 Categories: News

Once a year malaria research groups in the Netherlands come together to share their newest results, discuss future plans and collaborative efforts. This year this event was organised…

Dr. Sameera Patel is joining TropIQ as the first virologist in the laboratories.

By Jessica Konijnenburg21/01/201819/02/2018 Categories: News

Dr. Patel is a virologist who has worked at the University in Cambridge and

TropIQ latest manuscript published today.

By Jessica Konijnenburg15/12/201712/01/2018 Categories: News

TropIQ publishes novel modelling method for predicting the effectiveness of drugs on malaria transmission. The publication “Modelling mosquito infection at natural parasite densities

Deeya Shankari Rajagopal joins the TropIQ team

By Jessica Konijnenburg05/09/201720/09/2017 Categories: News

Deeya is a master student from the HAN University of Applied Sciences and will be with us for two years.

Annemarie Barink joins TropIQs team

By Jessica Konijnenburg22/08/201722/08/2017 Categories: News

Annemarie is an HBO student and will stay with us for a six months internship.

TropIQ enters partnership to combat vector-borne diseases

By Jessica Konijnenburg13/07/201724/07/2017 Categories: News

TropIQ joins forces with Protinhi Therapeutics, Radboud University and the Radboud University Medical Center in a project aimed at the discovery of novel therapeutics for malaria, dengue and…

TropIQ co-authors nature communications publication.

By Jessica Konijnenburg11/07/201720/09/2017 Categories: News

TropIQ co-authors the publication “A potent series targeting the malarial cGMP-dependent protein

Godelieve Bosman joins the TropIQ team as a laboratory attendant

By Jessica Konijnenburg10/05/201722/08/2017 Categories: News

TropIQ team contributes to study on Plasmodium kinase inhibitor

By Jessica Konijnenburg26/04/201701/05/2017 Categories: News

The publication “Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.” came out today.

TropIQ receives price for Dutch innovative startup

By Monique06/12/201614/04/2017 Categories: News

TropIQ receives the Unilever Sustainable Innovation Prize for the Dutch innovative startup best contributing to the Sustainable Development Goals as put forward by the United Nations.

TropIQ staff co-authors publication on novel antimalarial compound

By Monique04/10/201619/04/2017 Categories: News

October 4, 2016. TropIQ staff co-author the study ‘Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling’ published in PloS Medicine today.

TropIQ is awarded with a ‘Pearl of the region’

By Monique15/09/201606/03/2017 Categories: News

TropIQ is awarded with a ‘Pearl of the region’ award by The Economic Board. Waarom roept The Economic Board ‘parels van de regio’ in het leven? De Board…

TropIQ staff co-authors paper in Nature

By Monique07/09/201606/03/2017 Categories: News

Nature publishes the paper ‘Diversity-oriented synthesis yields novel multistage antimalarial inhibitors’ that is co-authored by TropIQ staff. Antimalarial drugs have thus far beenchiefly derived from two sources—natural products…

Malaria Journal publishes our newest paper ” An inter-laboratory comparison of the Standard Membrane Feeding Assay”

By Jessica Konijnenburg05/09/201619/04/2017 Categories: News

Here the “gold standard” status for transmission blocking activity of antibodies, the standard membrane feeding assay (SMFA), is verified in two different laboratories. Read the article here.

Laura Pelser-Posthumus joins the TropIQ as a laboratory attendant

By Jessica Konijnenburg01/06/201619/04/2017 Categories: News

TropIQ moves to different location

By Jessica Konijnenburg31/05/201619/04/2017 Categories: News

TropIQ has moved to a brand new laboratory at the Noviotech campus in Nijmegen, The Netherlands.

Malaria Journal publishes our contribution to the development of a novel malaria cocktail vaccine.

By Jessica Konijnenburg17/05/201619/04/2017 Categories: News

Read full article here. 

Marie Miglianico joins the TropIQ team as a scientist

By Jessica Konijnenburg09/05/201619/04/2017 Categories: News

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