Our team aids the discovery of a new anti-malarial scaffold. By Angelika Sturm31/08/202131/08/2021 Categories: News Due to the continuing rise of resistances against commonly used medication, new anit-malarials are needed to combat the disease. This publication suggests Quinazolinone-2-carboxamide derivatives as a novel malaria…
Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials By Angelika Sturm31/08/202131/08/2021 Categories: Publications Laleu B., et al., J Med Chem. 2021 Aug 26 ABSTRACT A phenotypic high-throughput screen allowed discovery of quinazolinone-2-carboxamide derivatives as a novel antimalarial scaffold. Structure-activity relationship studies…